The group is concerned with the development of new techniques for measuring multidimensional information in small biological objects such as cells, cell organelles, molecules or other biologically relevant structures. We want to elucidate how molecules interact in living cells at certain locations (e.g. in cell organelles) and at certain times (e.g. after stimulation by another molecule). To achieve this goal, we use molecules that can be switched between different fluorescent states by excitation with light of different wavelengths. If associated state transitions are saturated, the resulting nonlinear dependencies can be used to achieve theoretically unlimited resolution, for example by structured illumination (SI).
Further information on the working group can be found here.